Pierce Brosnans daughter Charlotte 41 dies of ovarian cancer the same ...

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James Bond actor Pierce Brosnan is mourning the tragic death of his daughter who succumbed to the same disease that killed her mother and her grandmother.

Charlotte Brosnan 41 a mother of two died of ovarian cancer last week in London.

Pierce Brosnan the Irish actor who starred in four 007 films lost his wife Cassandra Harris to the disease in 1991. Her mother Charlotte s grandmother also died from ovarian cancer.

Ron Galella/WireImage Pierce Brosnan is seen with his late wife Cassandra Harris an Australian actress and former Bond girl at the 42nd Annual Golden Globe Awards in 1991 the same year she died from ovarian cancer.

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On June 28 at 2 p.m. my darling daughter Charlotte Emily passed on to eternal life having succumbed to ovarian cancer Brosnan 60 said in a statement.

She was surrounded by her husband Alex children Isabella and Lucas and brothers Christopher and Sean.

Ron Galella Ltd./WireImage Pierce Brosnan center flanked by son Christopher and daughter Charlotte attend the 49th Annual Golden Globe Awards in January 1992 at Beverly Hilton Hotel in Beverly Hills Calif. one year after the children's mother Cassandra Harris died of ovarian cancer. Charlotte died of the same disease last week according to the actor.

Charlotte fought her cancer with grace and humility courage and dignity. Our hearts are heavy with the loss of our beautiful dear girl he said.

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We pray for her and that the cure for this wretched disease will be close at hand.

Ron Galella Ltd./WireImage Pierce Brosnan and daughter Charlotte attend the afterparty for Sting's Ten Summoner's Tales tour at the Greek Theatre in May 1993 at Spago in West Hollywood Calif. Charlotte died last week of ovarian cancer the same disease that claimed her mother.

Brosnan was filming spy thriller November Man in Eastern Europe when he rushed back to his daughter's bedside the Telegraph reports.

Charlotte's mother Cassandra who was an Australian actress and former Bond girl had two children from a previous marriage when she wed Brosnan in 1980 Charlotte and Christopher.

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Richard Corkery From left Pierce Brosnan daughter Charoltte and son Christoper attend the party for the book 'Virgin The Literary and Photographic Expose of Virgin Records' at New York restaurant Elaine's.

But Brosnan adopted the kids and they took his last name after their father died in 1986.

We just clicked as a family Brosnan told the Daily Express earlier this year. Charlotte and Chris have just been amazing in my life.

In Brosnan's new film Love Is All You Need the actor plays a widower who falls in love with a hairdresser suffering from cancer.

Dave M. Benett/Getty Images Pierce Brosnan and his daugher Charlotte posse for the paparazzi at The Orange British Academy Film Awards in February 2006.

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The role easily drew upon the personal hardships and tragedies he's had to rise against in his own life as he told the Mirror Online earlier this year.

I went through it all very publicly Brosnan said. Such things draw a mark across your heart and it s always a part of your life.

To watch someone you love have their life eaten away bit by bit by this insidious and horrid disease becomes an indelible part of your psyche.

Cassandra died in 1991 after becoming ill while filming a movie in India in 1987. Brosnan was left to raise their then 8 year old son Sean who grew up to become an actor himself.

Charlotte is survived by her husband Alex and her children Isabella 15 and Lucas 8.

Brosnan has two children Dylan 16 and Paris 12 with his second wife journalist Keely Shaye Smith whom he's referred to as his guiding North Star.

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